Home > School of Medical Science and Technology > Nishant Chakravorty
Associate Professor
School of Medical Science and Technology
If life is a story, then genetics is its language. Surprisingly, the script for this language, has only four alphabets (A, G, C and T for DNA and A, G, C and U for RNA). This simplicity ingrained in the most complex language of the mortal world has always baffled me as a scientist. I am primarily interested in decrypting the script of life and mastering it modulate health and disease. Decoding the secret language will allow us to develop newer strategies to counter pathophysiological challenges in human beings by encoding and packaging new information in life?s own language. My earlier work involved studying the role of small RNA molecules (known as microRNAs) in the interactions of bone cells with microroughened titanium implant surfaces. Presently I am developing a research lab in the field of regenerative medicine wherein I?ll be using molecular biology tools to study human pathophysiological conditions and attempt to identify therapeutic tools.
Comparison of oral dydrogestrone with progesterone gel and micronized progesterone for luteal support in 1,373 women undergoing in vitro fertilization: a randomized clinical study by Ashalatha Ganesh, Nishant Chakravorty, Rashmi Mukherjee, Sourendrakanta Goswami, Koel Chaudhury and Baidyanath Chakravarty Fertility and Sterility 95 (6) 1961-5 (2011)
Methods in Molecular Biology by by Yinghong Zhou, Nishant Chakravorty, Yin Xiao and Wenyi Gu Mesenchymal stem cells and nano-structured surfaces 133-48 (2013)
Alteration of the C-terminal ligand specificity of the Erbin PDZ domain by allosteric mutational effects by Javier Murciano-Calles, Megan E. McLaughlin, Ariel Erijman, Yogesh Hooda, Nishant Chakravorty, Jose C. Martinez, Julia M. Shifman and Sachdev S. Sidhu Journal of Molecular Biology 426 (21) 3500-8 (2014)
Pro-osteogenic topographical cues promote early activation of osteoprogenitor differentiation via enhanced TGFβ, Wnt and Notch signaling by by Nishant Chakravorty, Stephen Hamlet, Anjali Jaiprakash, Ross Crawford, Adekunle Oloyede, Mohammed Alfarsi, Yin Xiao and Saso Ivanovski Clinical and Oral Implants Research 25 (4) 475-86 (2014)
Lithium release from β-tricalcium phosphate inducing cementogenic and osteogenic differentiation of both hPDLCs and hBMSCs by Pingping Han, Mengchi Xu, Jiang Chang, Nishant Chakravorty, Chengtie Wu and Yin Xiao Biomaterials Science (9) 1230-43 (2014)
Computational pharmacokinetics and in vitro-in vivo correlation of anti-diabetic synergistic phyto-composite blend by Baishakhi De, Koushik Bhandari, Nishant Chakravorty, Ranjan Mukherjee, Rohit Gundamaraju, Rajeev K Singla, Prakash Katakam, Shanta K Adiki, Biswajoy Ghosh, Analava Mitra World Journal of Diabetes 6 (11) 1179-85 (2015)
Analyzing microRNA mediated regulation of fetal hemoglobin in beta-thalassemia using miRnalyze, a novel bioinformatics tool by Das S. S., James M. , Paul S. , Chakravorty N. Scientific Devices, Technology Applications & Community Linkage - (2017)
Mechanistic insights on long non-coding RNA (lncRNA)-mediated ceRNA network in fetal hemoglobin regulation Anusandhan National Research Foundation (ANRF)
Mechanistic investigation of the complex inter-relationship between HbE/Beta-thalassemia and protozoan parasite infections with HLA association Indian Council of Medical Research (ICMR)
SARS-CoV-2 and endothelium: In vitro and in vivo study into pathogenesis of vaccine induced thrombotic thrombocytopenia due to spike protein and vaccine-induced anti- PF-4antibodies and their interactions with endothelium INDIAN COUNCIL OF MEDICAL RESEARCH (ICMR)
Building the Evidence Base for Maternal Immunization to Protect Indian Infants from Lower Respiratory Tract Infections DBT/Wellcome Trust DBT, India Alliance
Vascular remodelling in cancer patients: Role of BRAP gene in the vascular smooth muscle cells after Chemotherapy-associated vascular dysfunction INDIAN COUNCIL OF MEDICAL RESEARCH (ICMR)
Development of customized implants via powder metallurgy process Science and Engineering Research Board (SERB)
Nanoengineered 3D Printed Thinner BRS for Controlled Degradation, Efficient Endothelialization, Antithrombotic, and vSMC-Antiproliferative: An Indigenous Approach to Treat Atherosclerosis (3DNanoResStent) INDIAN COUNCIL OF MEDICAL RESEARCH (ICMR)
Developing Human Bone mimetic 3D Bio-printed Organoid Models for Drug / Toxicology Screening: Characterizing it with Advanced Imaging Scheme for Promotion of Academic and Research Collaboration (SPARC), Apex Committee of SPARC
Prasanna Kumar Byram
Area of Research: Tissue Engineering
Motiur Rahaman
Area of Research: New Approaches to Manage Beta-thalassemia
Lopa Mudra Das
Area of Research: Development of a bioadhesive material for medical applications
Mandrita Mukherjee
Area of Research: Genetic modifiers of beta-thalassemia
Shatarupa Bhattacharya
Area of Research: Application of molecular biology approaches for disease management
Surajit Kundu
Area of Research: Medical Image Processing
Subhangi Basu
Area of Research: Beta-thalassemia and Cardiovascular complications
Dipanjana Ghosh
Area of Research: Mechanistic insights into Beta-thalassemia and complications
Murali Mohan Mishra
Area of Research: Lipid Nanomaterials
Anu Agarwal
Area of Research: Molecular mechanisms involved in Beta-thalassemia
Debesh Harh
Area of Research: Tissue Engineering
Subhra Bhattacharyya
Area of Research: Alternate mechanisms for management of beta-thalassemia
